Pomerantsev A P, Domaradskiĭ I V, Doronin I P, Ershov Iu V
Mol Gen Mikrobiol Virusol. 1991 Jul(7):12-5.
Hybrid plasmids containing the fragments of Francisella tularensis chromosomal DNA and capable of tet-gene expression both in Escherichia coli and Francisella tularensis cells were constructed. The regions of francisella chromosomal DNA binding the RNA-polymerases of Escherichia coli and Francisella tularensis were found by the electron microscopy technique. Interconnection of those regions with the expression of tet-gene of the hybrid plasmids was demonstrated.