Kleyweg R P, van der Meché F G, Schmitz P I
Department of Neurology, University Hospital Rotterdam-Dijkzigt, The Netherlands.
Muscle Nerve. 1991 Nov;14(11):1103-9. doi: 10.1002/mus.880141111.
In studies of Guillain-Barré syndrome, functional deficit is usually assessed according to a functional scale consisting of several categories. The level of interobserver agreement in this scoring method is not known; furthermore, this method seems to be insensitive when applied to bedridden and artificially ventilated patients. We have developed an additional score (MRC-sumscore), reflecting muscle strength in general. Both scoring methods, tested in Guillain-Barré patients, have an almost perfect interobserver agreement. For the functional score kappa = 0.85, and for the MRC-sumscore r2 = 0.96. The MRC-sumscore is easily assessed and more sensitive than the functional score when patients are bedridden or artificially ventilated.
在吉兰 - 巴雷综合征的研究中，功能缺陷通常根据一个由几个类别组成的功能量表来评估。这种评分方法中观察者间的一致性水平尚不清楚；此外，当应用于卧床和使用人工呼吸机的患者时，这种方法似乎不敏感。我们开发了一个额外的评分（医学研究委员会总分，MRC - sumscore），总体反映肌肉力量。在吉兰 - 巴雷患者中测试的这两种评分方法，观察者间的一致性几乎完美。功能评分的kappa值为0.85，医学研究委员会总分的r²值为0.96。当患者卧床或使用人工呼吸机时，医学研究委员会总分易于评估且比功能评分更敏感。
