Sharma Rajnish, Tewari K N, Bhatnagar Anuj, Mondal Anupam, Mishra Anil K, Singh Ajay K, Chopra M K, Rawat Harish, Kashyap Ravi, Tripathi R P
Department of Nuclear Medicine, Institute of Nuclear Medicine and Allied Sciences (INMAS), Lucknow Road, Delhi 110054, India.
Clin Nucl Med. 2007 May;32(5):367-70. doi: 10.1097/01.rlu.0000259322.31974.e8.
Tc-99m MDP and Tc-99m ciprofloxacin scans were performed in 14 patients with suspected tubercular bone disease and in 2 cases of nontubercular bone infection. In 5 patients the findings were true negative. There were no false positives and 1 was false negative. The sensitivity, specificity, and positive predictive value were found to be 93, 71, and 87.5%, respectively, for detection of bone tubercular lesions. However, the test does not distinguish TB osteomyelitis from other types of osteomyelitis. Delayed 24 hour scans were found useful to differentiate between inflammatory and infective lesions. The aim of this study was to evaluate the usefulness of the Tc-99m ciprofloxacin scan as a means to detect tubercular bone disease.
对14例疑似结核性骨病患者和2例非结核性骨感染患者进行了锝-99m亚甲基二膦酸盐（Tc-99m MDP）和锝-99m环丙沙星扫描。5例患者检查结果为真阴性。无假阳性，1例假阴性。检测骨结核病变的敏感性、特异性和阳性预测值分别为93%、71%和87.5%。然而，该检查无法区分结核性骨髓炎与其他类型的骨髓炎。发现延迟24小时扫描有助于鉴别炎性病变和感染性病变。本研究的目的是评估锝-99m环丙沙星扫描作为检测结核性骨病手段的有效性。
