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医学重症监护病房中的前瞻性姑息治疗:对特定高危患者住院时间的影响。

Proactive palliative care in the medical intensive care unit: effects on length of stay for selected high-risk patients.

作者信息

Norton Sally A, Hogan Laura A, Holloway Robert G, Temkin-Greener Helena, Buckley Marcia J, Quill Timothy E

机构信息

School of Nursing, University of Rochester Medical Center, Rochester, NY, USA.

出版信息

Crit Care Med. 2007 Jun;35(6):1530-5. doi: 10.1097/01.CCM.0000266533.06543.0C.

Abstract

OBJECTIVE

The purpose of this study was to examine the effect of proactive palliative care consultation on length of stay for high-risk patients in the medical intensive care unit (MICU).

DESIGN

A prospective pre/post nonequivalent control group design was used for this performance improvement study.

SETTING

Seventeen-bed adult MICU.

PATIENTS

Of admissions to the MICU, 191 patients were identified as having a serious illness and at high risk of dying: 65 patients in the usual care phase and 126 patients in the proactive palliative care phase. To be included in the sample, a patient had to meet one of the following criteria: a) intensive care admission following a current hospital stay of >or=10 days; b) age >80 yrs in the presence of two or more life-threatening comorbidities (e.g., end-stage renal disease, severe congestive heart failure); c) diagnosis of an active stage IV malignancy; d) status post cardiac arrest; or e) diagnosis of an intracerebral hemorrhage requiring mechanical ventilation.

INTERVENTIONS

Palliative care consultations.

MEASUREMENTS AND MAIN RESULTS

Primary measures were patient lengths of stay a) for the entire hospitalization; b) in the MICU; and c) from MICU admission to hospital discharge. Secondary measures included mortality rates and discharge disposition. There were no significant differences between the usual care and proactive palliative care intervention groups in respect to age, gender, race, screening criteria, discharge disposition, or mortality. Patients in the proactive palliative care group had significantly shorter lengths of stay in the MICU (8.96 vs. 16.28 days, p = .0001). There were no differences between the two groups on total length of stay in the hospital or length of stay from MICU admission to hospital discharge.

CONCLUSIONS

Proactive palliative care consultation was associated with a significantly shorter MICU length of stay in this high-risk group without any significant differences in mortality rates or discharge disposition.

摘要

目的

本研究旨在探讨前瞻性姑息治疗会诊对医疗重症监护病房(MICU)高危患者住院时间的影响。

设计

本绩效改进研究采用前瞻性前后非等效对照组设计。

地点

拥有17张床位的成人MICU。

患者

在入住MICU的患者中,191例被确定患有严重疾病且死亡风险高:65例处于常规护理阶段,126例处于前瞻性姑息治疗阶段。要纳入样本,患者必须符合以下标准之一:a)当前住院时间≥10天后入住重症监护病房;b)年龄>80岁且存在两种或更多危及生命的合并症(如终末期肾病、严重充血性心力衰竭);c)诊断为活跃的IV期恶性肿瘤;d)心脏骤停后;或e)诊断为需要机械通气的脑出血。

干预措施

姑息治疗会诊。

测量指标及主要结果

主要指标为患者a)整个住院期间;b)在MICU的;c)从入住MICU到出院的住院时间。次要指标包括死亡率和出院处置情况。在年龄、性别、种族、筛查标准、出院处置或死亡率方面,常规护理组和前瞻性姑息治疗干预组之间无显著差异。前瞻性姑息治疗组患者在MICU的住院时间显著缩短(8.96天对16.28天,p = 0.0001)。两组在住院总时间或从入住MICU到出院的住院时间上无差异。

结论

在该高危组中,前瞻性姑息治疗会诊与MICU住院时间显著缩短相关,而死亡率或出院处置情况无显著差异。

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