Bosma T J, Croxson M C, Thomas M G
Department of Virology, Auckland Hospital.
N Z Med J. 1991 Nov 27;104(924):499-500.
The HIV-1 infection status of two HIV-1 antibody positive infants born to HIV-1 infected mothers was determined using the polymerase chain reaction. HIV-1 genomic sequences were not detected in the white blood cells of either infant suggesting that they were not infected. HIV-1 genomic sequences were detected in the white blood cells of the mothers of both infants and in cells from the one surviving father. These results confirm the value of the PCR detection method for assessing the HIV-1 infection status of infants born to HIV-1 antibody positive mothers.
采用聚合酶链反应确定了两名感染人类免疫缺陷病毒1型（HIV-1）的母亲所生的HIV-1抗体阳性婴儿的HIV-1感染状况。在两名婴儿的白细胞中均未检测到HIV-1基因组序列，这表明他们未被感染。在两名婴儿母亲的白细胞以及存活的父亲的细胞中检测到了HIV-1基因组序列。这些结果证实了PCR检测方法在评估HIV-1抗体阳性母亲所生婴儿的HIV-1感染状况方面的价值。
