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疑似免疫性血小板减少症时避免进行骨髓检查是否安全?

Is it safe to avoid bone marrow examination in suspected itp?

作者信息

Naithani Rahul, Kumar Rajat, Mahapatra M, Agrawal Neerja, Pati H P, Choudhry V P

机构信息

Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Pediatr Hematol Oncol. 2007 Apr-May;24(3):205-7. doi: 10.1080/08880010701198845.

DOI:10.1080/08880010701198845
PMID:17454791
Abstract

Two children with suspected ITP are described. One child was treated outside with corticosteroids and was diagnosed acute lymphoblastic leukemia. Another child was fresh and diagnosed as acute myeloid leukemia on bone marrow aspirate examination. Both the children had no physical or peripheral smear finding suggestive of leukemia. We suggest that a bone marrow examination is required in developing countries for evaluation of thrombocytopenia before labeling it an immune thrombocytopenic purpura.

摘要

本文描述了两名疑似免疫性血小板减少症(ITP)的儿童。一名儿童在院外接受了皮质类固醇治疗,后被诊断为急性淋巴细胞白血病。另一名儿童初诊时经骨髓穿刺检查被诊断为急性髓系白血病。这两名儿童均无提示白血病的体格检查或外周血涂片表现。我们建议,在发展中国家,对于血小板减少症患者,在诊断为免疫性血小板减少性紫癜之前,需要进行骨髓检查以评估病情。

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引用本文的文献

1
Re-evaluation of Need for Bone Marrow Examination in Patients with Isolated Thrombocytopenia Contributors.孤立性血小板减少症患者骨髓检查必要性的重新评估 贡献者
Indian J Hematol Blood Transfus. 2016 Jun;32(2):193-6. doi: 10.1007/s12288-015-0533-2. Epub 2015 Mar 28.
2
Guidelines on the diagnosis of primary immune thrombocytopenia in children and adolescents: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Guidelines Project: Associação Médica Brasileira - 2012.儿童和青少年原发性免疫性血小板减少症诊断指南:巴西血液学、血液治疗和细胞治疗协会指南项目:巴西医学协会 - 2012年。
Rev Bras Hematol Hemoter. 2013;35(5):358-65. doi: 10.5581/1516-8484.20130105.