Huang Adam, Roy Dave A, Summers Ronald M, Franaszek Marek, Petrick Nicholas, Choi J Richard, Pickhardt Perry J
Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892-1182, USA.
Radiology. 2007 May;243(2):551-60. doi: 10.1148/radiol.2432060353.
This HIPAA-compliant study, with institutional review board approval and informed patient consent, was conducted to retrospectively develop a teniae coli-based circumferential localization method for guiding virtual colon navigation and colonic polyp registration. Colonic surfaces (n = 72) were depicted at computed tomographic (CT) colonography performed in 36 patients (26 men, 10 women; age range, 47-72 years) in the supine and prone positions. For 70 (97%) colonic surfaces, the tenia omentalis (TO), the most visible of the three teniae coli on a well-distended colonic surface, was manually extracted from the cecum to the descending colon. By virtually dissecting and flattening the colon along the TO, the authors developed a localization system involving 12 grid lines to estimate the circumferential positions of polyps. A sessile polyp would most likely (at 95% confidence level) be found within +/-1.2 grid lines (one grid line equals 1/12 the circumference) with use of the proposed method. By orienting and positioning the virtual cameras with use of the new localization system, synchronized prone and supine navigation was achieved. The teniae coli are extractable landmarks, and the teniae coli-based circumferential localization system helps guide virtual navigation and polyp registration at CT colonography.
这项符合健康保险流通与责任法案(HIPAA)的研究,经机构审查委员会批准并获得患者知情同意后开展,旨在回顾性地开发一种基于结肠带的圆周定位方法,用于指导虚拟结肠导航和结肠息肉配准。在36例患者(26例男性,10例女性;年龄范围47 - 72岁)仰卧位和俯卧位的计算机断层扫描(CT)结肠成像中描绘了结肠表面(n = 72)。对于70个(97%)结肠表面,网膜带(TO),即在充分扩张的结肠表面上三条结肠带中最明显的一条,从盲肠到降结肠进行了手动提取。通过沿TO对结肠进行虚拟解剖和平展,作者开发了一个包含12条网格线的定位系统,以估计息肉的圆周位置。使用所提出的方法,无蒂息肉最有可能(在95%置信水平)出现在±1.2条网格线内(一条网格线等于周长的1/12)。通过使用新的定位系统对虚拟相机进行定向和定位,实现了俯卧位和仰卧位的同步导航。结肠带是可提取的标志,基于结肠带的圆周定位系统有助于在CT结肠成像中指导虚拟导航和息肉配准。