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[非胰岛素依赖型糖尿病合并中度肥胖男性患者的血脂及胰岛素血水平模式]

[Pattern of plasma lipids and insulin blood levels in male patients with non-insulin-dependent diabetes mellitus and moderate obesity].

作者信息

Zurro Hernández J, Hâncu N, Lobón Cerviá C, Veresiu I A, Suciu I, Romero Bobillo E, Dobre L, Jeicán D

机构信息

Sección de Endocrinología, Hospital Universitario de Valladolid.

出版信息

Rev Clin Esp. 1991 Sep;189(4):172-4.

PMID:1745803
Abstract

The goal of the present work is the study of the plasmatic lipid profile in non insulin dependent diabetes mellitus (NIDDM) patients with abdominal obesity (AO), comparing them the NIDDM patients without AO and with OA persons without NIDDM. For that purpose we developed a methodology in which we have studied the body mass index (BMI: kg/m2) the hip-waist index (HWI) (0.95 = AO), lipid parameters, hydrocarbon, titers and serum insulin levels. The results are referred to four groups where we can throw into relief a statistically significant increase in triglycerides and a marked decrease in HDL cholesterol in OA and DM patients when compared to the group with AO without MD or to the group with MD without AO. Based on the results obtained the conclusions can be summarized as follows: The presence of abdominal obesity is a factor that favors the appearance of high levels of serum triglycerides and low levels of HDL-cholesterol in NIDDM. On the other hand, DM is a factor that increases the levels of triglycerides with low levels of HDL-cholesterol which already exist in AO.

摘要

本研究的目的是研究腹型肥胖(AO)的非胰岛素依赖型糖尿病(NIDDM)患者的血浆脂质谱,并将其与无AO的NIDDM患者以及无NIDDM的OA患者进行比较。为此,我们开发了一种方法,其中研究了体重指数(BMI:kg/m²)、髋腰比(HWI)(HWI≥0.95为AO)、脂质参数、烃类、滴度和血清胰岛素水平。结果分为四组,与无糖尿病的腹型肥胖组或无腹型肥胖的糖尿病组相比,腹型肥胖和糖尿病患者的甘油三酯有统计学意义的显著升高,高密度脂蛋白胆固醇显著降低。根据所得结果,结论可总结如下:腹型肥胖的存在是导致NIDDM患者血清甘油三酯水平升高和高密度脂蛋白胆固醇水平降低的一个因素。另一方面,糖尿病是一个会使腹型肥胖患者已有的甘油三酯水平升高、高密度脂蛋白胆固醇水平降低的因素。

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Rev Clin Esp. 1991 Sep;189(4):172-4.
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