Nakamura S, Okada I, Mizuno J, Nishida S
Can J Microbiol. 1977 May;23(5):601-6. doi: 10.1139/m77-087.
A mitomycin C induced lysate of Clostridium perfringens strain KZ219 was lytic to 50 strains of C. perfringens of types A-E, and three strains of C. plagarum. The lysin was active against only 2 out of 87 strains of 51 other clostridial species. The optimum pH of the lytic agent was 5.5. The activity was largely inactivated by proteolytic enzymes, and nearly completely inactivated by heating at 60 degrees C for 5 min.
丝裂霉素C诱导的产气荚膜梭菌KZ219菌株裂解物对50株A-E型产气荚膜梭菌及3株双酶梭菌具有溶菌作用。该溶菌素仅对51种其他梭菌属中的87株菌株中的2株有活性。溶菌剂的最适pH值为5.5。其活性在很大程度上被蛋白水解酶灭活,在60℃加热5分钟几乎完全失活。