Abe Tsugio, Murakami Atsushi, Nakajima Noriyuki, Inoue Tsuneo, Ohde Shigenori, Miwa Masato, Ueda Yoshihiko, Kawabata Kazuyoshi, Watanabe Kensuke
Department of Otorhinolaryngology, Dokkyo Medical University Koshigaya Hospital, 2-1-50 Minamikoshigaya, Koshigaya, Saitama 343-8555, Japan.
Auris Nasus Larynx. 2007 Sep;34(3):393-6. doi: 10.1016/j.anl.2007.01.013. Epub 2007 Apr 24.
The first case of oncocytic carcinoma which arose from the inferior turbinate of the nasal cavity with orbital invasion through the nasolacrimal canal and widespread lymph node metastases in the neck and face is reported here. The tumor metastasized rapidly, spread widely to the whole neck and face, and produced tumor emboli in the lymphatics and extranodal extension by rupture of the lymph node capsule in the absence of clinically palpable regional lymph node enlargement. We think the oncocytic carcinoma of the nasal cavity may be a high-grade malignancy tumor.
本文报告了首例起源于鼻腔下鼻甲的嗜酸细胞癌,该肿瘤经鼻泪管侵犯眼眶,并在颈部和面部出现广泛的淋巴结转移。肿瘤转移迅速,广泛扩散至整个颈部和面部,在临床上未触及区域淋巴结肿大的情况下,通过淋巴结包膜破裂在淋巴管内产生肿瘤栓子并出现结外扩散。我们认为鼻腔嗜酸细胞癌可能是一种高级别恶性肿瘤。