Schmid E R
Institut für Anästhesiologie, Universitätsspital Zürich.
Ther Umsch. 1991 Jun;48(6):365-73.
Cardiac complications are the major cause of morbidity and mortality in patients undergoing noncardiac operations. The perioperative risk of adverse cardiac events is particularly high in patients with significant coronary artery disease, heart failure or critical aortic stenosis. Prolonged intraperitoneal and intrathoracic operations, major vascular surgery, emergency procedures, and intraoperative hypotension and tachycardia promote and increase incidence and severity of cardiac complications. Recent experience has shown, however, that elective noncardiac operations can be performed with justifiable risk even in patients with endstage cardiac disease awaiting heart transplantation. Surgery, if indicated, can thus nowadays hardly be denied even in the presence of high cardiac risk. Successful anesthetic management requires detailed information about the cause and severity of the underlying disease, thorough understanding of its specific hemodynamic particularities, indepth knowledge about hemodynamic effects and interactions of anesthetic drugs, and experience with extended hemodynamic monitoring. Anesthetic choice by itself appears to be of minor significance. Cardiac surgery prior to major elective noncardiac procedures is advocated in patients with significant coronary artery disease or severe valve lesions. The incidence of life-threatening cardiac complications is particularly high in the postoperative period; prolonged hemodynamic monitoring in an intensive care unit is therefore mandatory.
心脏并发症是接受非心脏手术患者发病和死亡的主要原因。在患有严重冠状动脉疾病、心力衰竭或严重主动脉瓣狭窄的患者中,围手术期发生不良心脏事件的风险特别高。长时间的腹腔和胸腔内手术、大血管手术、急诊手术以及术中低血压和心动过速会促使并增加心脏并发症的发生率和严重程度。然而,最近的经验表明,即使是等待心脏移植的终末期心脏病患者,进行择期非心脏手术也具有合理的风险。因此,如今即使存在高心脏风险,如果有手术指征,手术也很难被拒绝。成功的麻醉管理需要有关基础疾病的病因和严重程度的详细信息,对其特定血流动力学特点的透彻理解,对麻醉药物的血流动力学效应和相互作用的深入了解,以及扩展血流动力学监测的经验。麻醉方式本身似乎意义不大。对于患有严重冠状动脉疾病或严重瓣膜病变的患者,主张在进行择期非心脏大手术之前先进行心脏手术。危及生命的心脏并发症在术后发生率特别高;因此,在重症监护病房进行长时间的血流动力学监测是必不可少的。