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早期胃癌的外科治疗

Surgical treatment of early gastric cancer.

作者信息

Nomura Sachiyo, Kaminishi Michio

机构信息

Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

出版信息

Dig Surg. 2007;24(2):96-100. doi: 10.1159/000101895. Epub 2007 Apr 25.

Abstract

Around half the cases of gastric cancer are found in the early stage in Japan. With an expected good prognosis, many treatment options have been developed to maintain a good quality of life of the patients after the treatment. Gastric cancer is diagnosed with endoscopy, and the depth of invasion is diagnosed with endoscopy and endoscopic ultrasound. One of the new treatments is endoscopic submucosal dissection. Improvements in surgical treatment are minimizing lymph node dissection, reconstruction methods, laparoscopy-assisted surgery, and sentinel node navigation surgery. Minimizing lymph node dissection for early gastric cancer is well described in the Guidelines for Gastric Cancer Treatments. Pylorus-preserving gastrectomy, jejunal interposition, pouch reconstruction, and Roux-en-Y reconstruction after distal gastrectomy are improvements in reconstruction after gastrectomy. More and more surgeons start laparoscopy-assisted gastrectomy with lymph node dissection. Even with these improvements, the 5-year survival of early gastric cancer is more than 90% in Japan. Further improvements would be possible in the future.

摘要

在日本,约一半的胃癌病例在早期被发现。鉴于预期预后良好,已开发出多种治疗方案,以在治疗后维持患者的良好生活质量。胃癌通过内窥镜检查进行诊断,而浸润深度则通过内窥镜检查和超声内镜进行诊断。新型治疗方法之一是内镜黏膜下剥离术。手术治疗的改进包括尽量减少淋巴结清扫、重建方法、腹腔镜辅助手术和前哨淋巴结导航手术。早期胃癌的最小化淋巴结清扫在《胃癌治疗指南》中有详细描述。保留幽门胃切除术、空肠间置术、袋状重建术以及远端胃切除术后的Roux-en-Y重建术是胃切除术后重建方面的改进。越来越多的外科医生开始进行腹腔镜辅助胃癌根治术并清扫淋巴结。即便有这些改进,日本早期胃癌的5年生存率仍超过90%。未来可能会有进一步的改进。

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