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评估13C尿素呼气试验和粪便抗原免疫测定法在冈比亚婴儿中检测幽门螺杆菌感染的情况。

Evaluation of 13C-urea breath test and fecal antigen immunoassay to detect Helicobacter pylori infection in Gambian infants.

作者信息

Jones Rhys T, Darboe Momodou K, Doherty Conor P, MacKay William G, Weaver Lawrence T, Campbell David I, Thomas Julian E

机构信息

University of Newcastle, School of Clinical Medical Sciences, Newcastle-upon-Tyne, UK.

出版信息

J Pediatr Gastroenterol Nutr. 2007 May;44(5):650-2. doi: 10.1097/MPG.0b013e31803e172e.

DOI:10.1097/MPG.0b013e31803e172e
PMID:17460504
Abstract

Helicobacter pylori colonization was measured by [13C]-urea breath test in 198 Gambian infants and by fecal enzyme-linked immunosorbent assay in 52 of the 198 at ages 2, 5, and 12 months. By 12 months there was good concordance between tests; 33 of 44 (75%) test results were positive by enzyme-linked immunosorbent assay, and 29 of 44 (66%) test results were positive by urea breath test. H. pylori colonization is common among Gambian infants, and noninvasive tests can provide a reliable means of diagnosis.

摘要

在198名冈比亚婴儿中,通过[13C] - 尿素呼气试验检测幽门螺杆菌定植情况;在这198名婴儿中的52名婴儿2个月、5个月和12个月大时,通过粪便酶联免疫吸附测定法进行检测。到12个月时,两种检测方法之间具有良好的一致性;酶联免疫吸附测定法检测的44例结果中有33例(75%)呈阳性,尿素呼气试验检测的44例结果中有29例(66%)呈阳性。幽门螺杆菌定植在冈比亚婴儿中很常见,非侵入性检测可提供可靠的诊断方法。

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引用本文的文献

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Non-invasive diagnostic tests for Helicobacter pylori infection.幽门螺杆菌感染的非侵入性诊断测试。
Cochrane Database Syst Rev. 2018 Mar 15;3(3):CD012080. doi: 10.1002/14651858.CD012080.pub2.
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Helicobacter pylori infection in pregnant women in four districts of Uganda: role of geographic location, education and water sources.乌干达四个地区孕妇的幽门螺杆菌感染:地理位置、教育程度和水源的作用。
BMC Public Health. 2014 Sep 4;14:915. doi: 10.1186/1471-2458-14-915.