Harrington Brian C
Southern Colorado Family Medicine Residency Program, St. Mary Corwin Medical Center, Pueblo, Colorado, USA.
Pediatr Dermatol. 2007 Mar-Apr;24(2):138-40. doi: 10.1111/j.1525-1470.2007.00360.x.
The hair collar sign has been described as a marker of cranial dysraphism, including encephaloceles, meningoceles, and heterotropic brain tissue. This report describes a male born with a hair collar sign who subsequently was found to have a Klippel-Feil anomaly, diastematomyelia, multiple segmental spine and rib anomalies, and a translocation between chromosomes 1 and 4; t(1;4) (q44;q10). While not previously documented, spine abnormalities may be an associated abnormality with the hair collar sign. Physicians should consider radiographic evaluation of the spine in all newborns with a hair collar sign, as well as genetic screening.
发领征已被描述为一种颅脊柱裂的标志，包括脑膨出、脊膜膨出和异位脑组织。本报告描述了一名出生时伴有发领征的男性，随后发现其患有Klippel-Feil畸形、脊髓纵裂、多节段脊柱和肋骨异常，以及1号和4号染色体之间的易位；t(1;4)(q44;q10)。虽然此前未见相关记录，但脊柱异常可能是发领征的一种相关异常情况。对于所有有发领征的新生儿，医生应考虑对其脊柱进行影像学评估以及基因筛查。
