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系统性硬化症中的面部皮下钙质沉着症和下颌骨吸收:一例报告

Facial subcutaneous calcinosis and mandibular resorption in systemic sclerosis: a case report.

作者信息

Alpöz E, Cankaya H, Güneri P

机构信息

Ege University School of Dentistry, Department of Oral Diagnosis and Radiology, Bornova, Izmir 35100, Turkey.

出版信息

Dentomaxillofac Radiol. 2007 Mar;36(3):172-4. doi: 10.1259/dmfr/25037311.

Abstract

Systemic sclerosis (SSc) is an autoimmune disease characterized by widespread fibrosis of subcutaneous connective tissue, causing serious complications with the involvement of other systems. Tight, firm skin is the main characteristic of SSc, causing extrinsic pressure and the obliteration of the vessels. This then leads to ischaemia and destruction of the underlying bone. This mechanism may also lead to bone resorption of the mandibular body as it affects other bones of the skeleton. To date, only two cases of reported calcinosis in the facial area have been observed. In this report, a rare case of SSc with both subcutaneous calcinosis and mandibular bone resorption is presented. The role of dental practitioners in the diagnosis of the disease with respect to the orofacial symptoms is also discussed.

摘要

系统性硬化症(SSc)是一种自身免疫性疾病,其特征为皮下结缔组织广泛纤维化,可累及其他系统并引发严重并发症。皮肤紧绷、坚硬是系统性硬化症的主要特征,会造成外部压力并导致血管闭塞。这进而会导致局部缺血以及深层骨骼的破坏。这种机制也可能导致下颌骨体的骨质吸收,因为它会影响骨骼的其他部位。迄今为止,仅观察到两例面部钙化的报告病例。在本报告中,呈现了一例罕见的同时伴有皮下钙化和下颌骨吸收的系统性硬化症病例。还讨论了牙科医生在针对口面部症状诊断该疾病方面的作用。

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