Sarnquist Clea C, Cunningham Shayna D, Sullivan Barbara, Maldonado Yvonne
Department of Pediatrics, Stanford University School of Medicine, Stanford, Calif, USA.
Am J Public Health. 2007 Jun;97(6):1041-6. doi: 10.2105/AJPH.2005.072371. Epub 2007 Apr 26.
The 1994 and 1995 US Public Health Service Guidelines regarding HIV testing and treatment for pregnant women and the resulting 1995 California law mandating an HIV test and treatment offer to every pregnant woman aim to reduce perinatal HIV transmission. However, the effectiveness of such policies after implementation is often unclear. We analyzed the association between these policies and offers of HIV tests and treatment to HIV-infected women in California.
Data from active, population-based surveillance of 496 HIV-infected women and their infants, collected from 1987 to 2002, were analyzed to compare rates of offers of HIV tests and treatment before and after 1996.
We found significant increases in offers of HIV tests (P<.001) and offers of treatment (P<.001) when we compared women who delivered between 1987 and 1995 with those who delivered between 1996 and 2002. Receipt of prenatal care was the major predictor of both test and treatment offer. A significant shift in reported HIV risk factors was also evident between the 2 groups.
Our findings of increased offers of HIV tests and treatment to HIV-infected pregnant women suggest that the national guidelines and the 1996 California law improved health care for these women, which may lessen the risk of perinatal HIV transmission.
1994年和1995年美国公共卫生服务部关于孕妇艾滋病毒检测和治疗的指南,以及由此产生的1995年加利福尼亚州法律规定对每位孕妇提供艾滋病毒检测和治疗,旨在减少围产期艾滋病毒传播。然而,这些政策实施后的效果往往不明确。我们分析了这些政策与加利福尼亚州向感染艾滋病毒的妇女提供艾滋病毒检测和治疗之间的关联。
分析了1987年至2002年期间对496名感染艾滋病毒的妇女及其婴儿进行的基于人群的主动监测数据,以比较1996年前后艾滋病毒检测和治疗的提供率。
当我们将1987年至1995年分娩的妇女与1996年至2002年分娩的妇女进行比较时,发现艾滋病毒检测的提供率(P<.001)和治疗的提供率(P<.001)有显著增加。接受产前护理是检测和治疗提供的主要预测因素。两组之间报告的艾滋病毒风险因素也有明显的转变。
我们发现向感染艾滋病毒的孕妇提供艾滋病毒检测和治疗的比例增加表明,国家指南和1996年加利福尼亚州法律改善了这些妇女的医疗保健,这可能会降低围产期艾滋病毒传播的风险。