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一名下肢肌阵挛患者在停用和使用抗癫痫药物治疗时的步态模式。

Gait patterns of a patient with myoclonus of a lower limb, when OFF and ON treatment with antiepileptic drugs.

作者信息

Cioni M, Iero I, Tornatore G, Cocilovo A, Belfiore A, Ferri R

机构信息

Department of Experimental and Clinical Pharmacology, Medical School, University of Catania, V.le A. Doria 6, I-95125 Catania, Italy.

出版信息

Neurol Sci. 2007 Apr;28(2):100-3. doi: 10.1007/s10072-007-0795-z.

Abstract

We describe kinematics, kinetics and electromyographic patterns of a patient with spinal myoclonus of the left lower limb, during walking. Gait analysis was performed when the patient was OFF and ON his treatment with antiepileptic drugs. When OFF, we mainly observed clonic bursts and out-of-phase activations of m. tibialis anterior and m. rectus femoris, with increased hip flexion, reduction of knee flexion during swing and excessive ankle dorsal flexion. Furthermore, large oscillations of knee moment of force and power during stance phase were also observed. These abnormal patterns markedly recovered when ON drugs.

摘要

我们描述了一名左下肢脊髓性肌阵挛患者在行走过程中的运动学、动力学和肌电图模式。在患者停用和使用抗癫痫药物治疗时进行了步态分析。停用药物时,我们主要观察到胫骨前肌和股直肌的阵挛性爆发和不同步激活,伴有髋部屈曲增加、摆动期膝关节屈曲减少以及踝关节过度背屈。此外,在站立期还观察到膝关节力矩和功率的大幅振荡。服用药物时,这些异常模式明显恢复。

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