Joiner M A, Asztalos Z, Jones C J, Tully T, Wu C-F
Department of Biological Sciences, University of Iowa, Iowa City, IA 52242, USA.
J Neurogenet. 2007 Jan-Jun;21(1-2):45-58. doi: 10.1080/01677060701247375.
The olfactory-jump response assay was used to analyze habituation in Drosophila mutants of potassium (K(+)) channel subunits. As with physiological assays of the giant fiber-mediated escape reflex, mutations at loci that encode K(+) channel subunits have distinct effects on habituating the olfactory-jump response. The data for slowpoke and ether à go-go indicate similar effects on habituation of the olfactory-jump response and the giant fiber-mediated escape. Habituation in the olfactory jump assay in Hyperkinetic and Shaker mutants was drastically different from the degree of defect in the giant fiber-mediated escape reflex, indicating differential control mechanisms underlying the two forms of non-associative conditioning.
嗅觉跳跃反应试验用于分析果蝇钾（K⁺）通道亚基突变体的习惯化。与巨纤维介导的逃避反射的生理学试验一样，编码K⁺通道亚基的基因座发生突变对嗅觉跳跃反应的习惯化有不同影响。慢poke和ether à go-go的试验数据表明，它们对嗅觉跳跃反应和巨纤维介导的逃避反应的习惯化有相似影响。多动症和震颤突变体的嗅觉跳跃试验中的习惯化与巨纤维介导的逃避反射的缺陷程度有很大不同，这表明两种非联合性条件反射形式有不同的控制机制。
