抗神经节苷脂抗体介导的钩端螺旋体性脑膜脑脊髓多发性神经炎

Anti-ganglioside antibodies-mediated leptospiral meningomyeloencephalopolyneuritis.

作者信息

Lepur Dragan, Himbele Josip, Klinar Igor, Vranjican Zoran, Barsic Bruno

机构信息

Department of Neuroinfections and Intensive Care Medicine, University Hospital for Infectious Diseases 'Dr. Fran Mihaljevic', Mirogojska, Zagreb. Croatia.

出版信息

Scand J Infect Dis. 2007;39(5):472-5. doi: 10.1080/00365540601034816.

DOI:10.1080/00365540601034816

PMID:17464876

Abstract

A case of leptospirosis complicated with meningo-myelo-encephalo-polyneuritis and nephrotic syndrome is presented. Anti-ganglioside antibodies were detected for the first time in a patient with neurological complications of leptospirosis. Possible pathogenic mechanisms and treatment options of these rare manifestations are discussed.

摘要

本文报告一例钩端螺旋体病并发脑膜脊髓脑多神经炎和肾病综合征的病例。在一名患有钩端螺旋体病神经并发症的患者中首次检测到抗神经节苷脂抗体。讨论了这些罕见表现的可能致病机制和治疗选择。