Lechan Ronald M, Fekete Csaba
Tupper Research Institute, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Tufts-New England Medical Center, Boston, MA 02111, USA.
Acta Biomed. 2007;78 Suppl 1:84-98.
Tanycytes comprise a heterogeneous population of specialized cells of glial origin that line the floor and ventrolateral walls of the third ventricle between the rostral and caudal limits of the hypothalamic median eminence. While morphologic and ultrastructural features suggest a role as barrier cells, creating separate compartments between the cerebrospinal fluid, median eminence and hypothalamus, tanycytes likely have multiple other important functions that have yet to be fully elucidated. Possibilities to consider are a role in neuroendocrine regulation including modulation of the hypothalamic-pituitary-thyroid axis during fasting and infection, regulation of reproductive function, particularly in seasonal breeders, and in feeding.
伸展细胞是一群起源于神经胶质的特殊细胞，具有异质性，它们排列在第三脑室底部和腹外侧壁，位于下丘脑正中隆起的头端和尾端界限之间。虽然形态学和超微结构特征表明伸展细胞具有屏障细胞的作用，在脑脊液、正中隆起和下丘脑之间形成独立的隔室，但伸展细胞可能还有许多其他重要功能尚未完全阐明。需要考虑的可能性包括在神经内分泌调节中的作用，如在禁食和感染期间对下丘脑 - 垂体 - 甲状腺轴的调节、生殖功能的调节，特别是在季节性繁殖动物中，以及在进食方面的调节。
