Turgut Mehmet, Meteoglu Ibrahim
Department of Neurosurgery, Adnan Menderes University Hospital, Aydin, Turkey.
J Neurosurg. 2007 Apr;106(4 Suppl):305-7. doi: 10.3171/ped.2007.106.4.305.
Teratomas and encephaloceles are both uncommon congenital malformations that originate near the midline in the head and neck. An encephalocele is an extracranial extension of intracranial structures through a defect in the skull, whereas a teratoma consists of tissue from all three embryonic germ layers and is a true congenital tumor. In the present study the authors describe the first reported case of a mature teratoma associated with an interparietal encephalocele presenting as a large midline subcutaneous mass in a newborn child. The appearance of these two pathological entities together suggests a common origin. The embryological significance of this finding is discussed, and the pertinent literature is reviewed.
畸胎瘤和脑膨出都是罕见的先天性畸形，起源于头颈部中线附近。脑膨出是颅内结构通过颅骨缺损向颅外延伸，而畸胎瘤由来自所有三个胚胎胚层的组织组成，是一种真正的先天性肿瘤。在本研究中，作者描述了首例报道的成熟畸胎瘤与顶间脑膨出相关的病例，该病例表现为一名新生儿的巨大中线皮下肿块。这两种病理实体同时出现提示有共同的起源。本文讨论了这一发现的胚胎学意义，并对相关文献进行了综述。
