Al-Qahtani Mohammed, Morris Brian, Dawood Shaheenah, Onerheim Ronald
Department of Surgery, McGill University Health Centre, Montreal, Quebec, Canada.
Can J Urol. 2007 Apr;14(2):3514-7.
Malignant mesothelioma involving the tunica vaginalis is an extremely rare tumor.
We describe a case of a 39-year-old man who initially presented with discomfort in the left testis and underwent resection of a hydrocele in the left testis. A pathology examination of a frozen section of a lesion on the tunica identified the lesion as mesothelioma, which was confirmed by a second pathology examination. No metastatic disease was found. The patient subsequently underwent a left radical orchiectomy and a partial scrotectomy, and has been disease free for 7 years.
The first case of malignant mesothelioma involving the tunica vaginalis, a structure embryologically derived from a layer of reflected peritoneum known as the "processus vaginalis," was reported in 1957. Only 73 cases were reported in the literature between 1966 and 1997. In up to 41% of cases, there is a positive history of asbestos exposure. Young age and localized disease are associated with a better prognosis. Radical orchiectomy limits recurrence, which usually occurs within 2 years, but may occur up to 15 years after surgery.
累及睾丸鞘膜的恶性间皮瘤是一种极其罕见的肿瘤。
我们描述了一名39岁男性的病例,他最初表现为左侧睾丸不适,随后接受了左侧睾丸鞘膜积液切除术。对鞘膜上病变的冰冻切片进行病理检查,将病变确定为间皮瘤,第二次病理检查证实了这一诊断。未发现转移病灶。该患者随后接受了左侧根治性睾丸切除术和部分阴囊切除术,至今已无病生存7年。
1957年报道了首例累及睾丸鞘膜的恶性间皮瘤,睾丸鞘膜是一种胚胎学上源自一层称为“鞘突”的腹膜反折的结构。1966年至1997年间,文献中仅报道了73例。高达41%的病例有石棉接触史。年轻和疾病局限与较好的预后相关。根治性睾丸切除术可减少复发,复发通常发生在2年内,但也可能在手术后长达15年时出现。