Annuar Bin Rapaee, Liew Chee Khoon, Chin Sze Piaw, Ong Tiong Kiam, Seyfarth M Tobias, Chan Wei Ling, Fong Yean Yip, Ang Choon Kiat, Lin Naing, Liew Houng Bang, Sim Kui Hian
Faculty of Medicine, University Malaysia Sarawak, Department of Cardiology, Sarawak General Hospital, Malaysia.
Eur J Radiol. 2008 Jan;65(1):112-9. doi: 10.1016/j.ejrad.2007.03.008. Epub 2007 Apr 26.
To compare the assessment of global and regional left ventricular (LV) function using 64-slice multislice computed tomography (MSCT), 2D echocardiography (2DE) and cardiac magnetic resonance (CMR).
Thirty-two consecutive patients (mean age, 56.5+/-9.7 years) referred for evaluation of coronary artery using 64-slice MSCT also underwent 2DE and CMR within 48h. The global left ventricular function which include left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVdV) and left ventricular end systolic volume (LVsV) were determine using the three modalities. Regional wall motion (RWM) was assessed visually in all three modalities. The CMR served as the gold standard for the comparison between 64-slice MSCT with CMR and 2DE with CMR. Statistical analysis included Pearson correlation coefficient, Bland-Altman plots and kappa-statistics.
The 64-slice MSCT agreed well with CMR for assessment of LVEF (r=0.92; p<0.0001), LVdV (r=0.98; p<0.0001) and LVsV (r=0.98; p<0.0001). In comparison with 64-slice MSCT, 2DE showed moderate correlation with CMR for the assessment of LVEF (r=0.84; p<0.0001), LVdV (r=0.83; p<0.0001) and LVsV (r=0.80; p<0.0001). However in RWM analysis, 2DE showed better accuracy than 64-slice MSCT (94.3% versus 82.4%) and closer agreement (kappa=0.89 versus 0.63) with CMR.
64-Slice MSCT correlates strongly with CMR in global LV function however in regional LV function 2DE showed better agreement with CMR than 64-slice MSCT.
比较使用64层多层螺旋CT（MSCT）、二维超声心动图（2DE）和心脏磁共振成像（CMR）对左心室（LV）整体和局部功能的评估。
连续32例（平均年龄56.5±9.7岁）因冠状动脉评估而行64层MSCT检查的患者在48小时内还接受了2DE和CMR检查。使用这三种方法测定包括左心室射血分数（LVEF）、左心室舒张末期容积（LVdV）和左心室收缩末期容积（LVsV）在内的左心室整体功能。在所有三种方法中对室壁节段运动（RWM）进行视觉评估。CMR作为64层MSCT与CMR以及2DE与CMR之间比较的金标准。统计分析包括Pearson相关系数、Bland-Altman图和kappa统计量。
64层MSCT在评估LVEF（r=0.92；p<0.0001）、LVdV（r=0.98；p<0.0001）和LVsV（r=0.98；p<0.0001）方面与CMR高度一致。与64层MSCT相比，2DE在评估LVEF（r=0.84；p<0.0001）、LVdV（r=0.83；p<0.0001）和LVsV（r=0.80；p<0.0001）方面与CMR呈中度相关。然而在RWM分析中，2DE显示出比64层MSCT更高的准确性（94.3%对82.4%），并且与CMR的一致性更紧密（kappa=0.89对0.63）。
64层MSCT在左心室整体功能方面与CMR有很强的相关性，然而在左心室局部功能方面，2DE与CMR的一致性比64层MSCT更好。
