Moreno Marcelo, Moreno André, Tomé Cindiamar
Department of Anatomy and Oncology Surgery, Universidade Comunitária Regional de Chapecó, UNOCHAPECO, Curso de Medicina, Chapecó, SC, Brazil.
Oral Oncol. 2008 Mar;44(3):305-8. doi: 10.1016/j.oraloncology.2006.12.015. Epub 2007 Apr 27.
Adenocarcinoma of the minor salivary gland (MSG) is a rare neoplasm. It represents about 2% of all MSG malignant tumours. It is more common in the palate and in females. This tumour occurs in a mean age of sixty and its mean size at presentation is 1.5cm. Microscopically, the neoplasms classified as adenocarcinoma not otherwise specified (NOS) are a histologically heterogeneous group: they vary from highly anaplastic adenocarcinoma to moderate and well-differentiated lesions. This report describes a case of adenocarcinoma of MSG occurring in the buccal mucosa of a 24-year-old male. The patient underwent a sentinel node biopsy as a staging tool in association with the primary surgical treatment. In the histological examination of sentinel lymph node (SLN) there was no evidence of metastatic disease. The patient presents no evidence of recurrent disease after 4years of follow-up. We believe that the use of SLN biopsy can be indicated in similar cases considering the tumoural biology (well-differentiated) because prospective randomized studies would be very difficult to be performed due to the rarity of this neoplasm.
小唾液腺腺癌是一种罕见的肿瘤。它约占所有小唾液腺恶性肿瘤的2%。在腭部和女性中更为常见。该肿瘤发病的平均年龄为60岁，就诊时的平均大小为1.5厘米。在显微镜下，分类为非特殊类型腺癌（NOS）的肿瘤在组织学上是一组异质性病变：从高度间变性腺癌到中度和高分化病变不等。本报告描述了一例发生在一名24岁男性颊黏膜的小唾液腺腺癌病例。患者接受了前哨淋巴结活检作为与原发性手术治疗相关的分期工具。在前哨淋巴结（SLN）的组织学检查中，没有转移疾病的证据。经过4年的随访，患者没有复发疾病的迹象。考虑到肿瘤生物学特性（高分化），我们认为在类似病例中可以使用前哨淋巴结活检，因为由于这种肿瘤罕见，很难进行前瞻性随机研究。
