缬更昔洛韦用于先天性巨细胞病毒感染：新生儿和婴儿血浆浓度的初步研究。
Valganciclovir for congenital CMV infection: a pilot study on plasma concentration in newborns and infants.
作者信息
Galli Luisa, Novelli Andrea, Chiappini Elena, Gervaso Paola, Cassetta Maria Iris, Fallani Stefania, de Martino Maurizio
机构信息
Departments of Pediatrics, University of Florence, Florence, Italy.
出版信息
Pediatr Infect Dis J. 2007 May;26(5):451-3. doi: 10.1097/01.inf.0000261111.90075.4d.
Abstract
The pharmacokinetics of valganciclovir were studied in 8 infants ranging in age from 4 to 90 days (mean 20 days). We suggest that doses of 15 mg/kg given twice daily may be suitable for neonates and young infants.
摘要
对8名年龄在4至90天（平均20天）的婴儿进行了缬更昔洛韦的药代动力学研究。我们建议，每日两次给予15mg/kg的剂量可能适用于新生儿和幼儿。
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