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Segregation analysis of autosomal fragile sites in three families with the fragile X chromosome.

作者信息

Barletta C, Ragusa R M, Garofalo G, Scillato F, Ruggeri M

机构信息

OASI Institute for Research on Mental Retardation and Brain Aging, Enna, Italy.

出版信息

Ann Genet. 1991;34(2):111-4.

PMID:1746880
Abstract

Fragile sites on chromosomes 9, at 9p21, 10, at 10q25 and 12, at 12q24, were found in the lymphocytes of some members of three families during the study for detection of a fragile X chromosome. The sites were found to be heritable and folato-sensitive. The genetic implications of these results are discussed.

摘要

相似文献

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引用本文的文献

1
Fragile sites, chromosomal lesions, tandem repeats, and disease.脆性位点、染色体病变、串联重复序列与疾病。
Front Genet. 2022 Nov 17;13:985975. doi: 10.3389/fgene.2022.985975. eCollection 2022.
2
Fragility Extraordinaire: Unsolved Mysteries of Chromosome Fragile Sites.脆性非凡:染色体脆性位点未解之谜。
Adv Exp Med Biol. 2017;1042:489-526. doi: 10.1007/978-981-10-6955-0_21.