Mills Tracey A, Baker Philip N, Wareing Mark
Division of Human Development, The University of Manchester, Manchester, UK.
Hypertens Pregnancy. 2007;26(2):201-10. doi: 10.1080/10601330701274824.
To determine whether delivery mode influences placental chorionic plate arterial and venous vascular reactivity.
Normal term placentas were obtained after vaginal delivery or cesarean section. Chorionic plate arterial and venous function was assessed by wire myography.
Sodium nitroprusside-induced arterial relaxation increased post cesarean section at 20% oxygen. Decreased U46619-induced venous contraction was observed in vaginal deliveries at 7% oxygen. Sodium nitroprusside-induced relaxation increased in vaginal delivery at 20% oxygen.
Delivery mode does not alter chorionic plate arterial vascular reactivity under physiological conditions, however venous reactivity was modified, a factor for consideration when interpreting functional experimental data.
确定分娩方式是否会影响胎盘绒毛膜板动脉和静脉血管反应性。
经阴道分娩或剖宫产术后获取足月正常胎盘。通过线肌描记法评估绒毛膜板动脉和静脉功能。
在20%氧气浓度下剖宫产术后硝普钠诱导的动脉舒张增加。在7%氧气浓度下经阴道分娩时观察到U46619诱导的静脉收缩减少。在20%氧气浓度下经阴道分娩时硝普钠诱导的舒张增加。
在生理条件下，分娩方式不会改变绒毛膜板动脉血管反应性，然而静脉反应性有所改变，这是在解释功能性实验数据时需要考虑的一个因素。
