Alexánderson Erick, Cruz Patricio, Sierra Carlos, Talayero José Antonio, Meave Aloha
Unidad PET-Ciclotrón, Facultad de Medicina, Universidad Nacional Autónoma de México, Imagen Cardiovascular, Instituto Nacional de Cardiologia "Dr. Ignacio Chávez", Mexico D. F.
Arch Cardiol Mex. 2006 Oct-Dec;76 Suppl 4:S111-20.
A complete evaluation of the patient with ischemic heart disease requires an anatomical and functional assessment of the myocardium and coronary arteries. Recent technological advances have allowed a quantitative and physiological evaluation of the cardiovascular system with Positron Emission Tomography (PET). This method is a valuable tool for the assessment of heart metabolism, myocardial perfusion, ventricular function, coronary blood flow, myocardial viability and endothelial function. One of the major limitations of a PET study is its low spatial resolution. Cardiac Computed Tomography (CCT) is an anatomic study used for coronary calcium quantification, evaluation of wall and lumen of coronary arteries, study of vascular permeability and assessment of composition, extension and severity of atherosclerotic plaques. The main limitation of CCT is the lack of functional information that is obtained with this technique. Both methods are complementary in many ways. That is the reason of the wide spread of PET-CT hybrid equipments that can provide very useful functional and anatomic information of patients with ischemic heart disease in a single exploration.
对缺血性心脏病患者进行全面评估需要对心肌和冠状动脉进行解剖学和功能评估。最近的技术进步使得利用正电子发射断层扫描(PET)对心血管系统进行定量和生理学评估成为可能。这种方法是评估心脏代谢、心肌灌注、心室功能、冠状动脉血流、心肌活力和内皮功能的宝贵工具。PET研究的主要局限性之一是其空间分辨率较低。心脏计算机断层扫描(CCT)是一种用于冠状动脉钙化定量、评估冠状动脉壁和管腔、研究血管通透性以及评估动脉粥样硬化斑块的组成、范围和严重程度的解剖学研究。CCT的主要局限性是缺乏通过该技术获得的功能信息。这两种方法在许多方面是互补的。这就是PET-CT混合设备广泛应用的原因,这种设备可以在一次检查中为缺血性心脏病患者提供非常有用的功能和解剖学信息。