Munk-Olsen Trine, Laursen Thomas Munk, Videbech Poul, Mortensen Preben Bo, Rosenberg Raben
National Centre for Register-Based Research, University of Aarhus, Aarhus C, Denmark.
Br J Psychiatry. 2007 May;190:435-9. doi: 10.1192/bjp.bp.106.026740.
Studies investigating mortality secondary to electroconvulsive therapy (ECT) are few.
To assess the risk of mortality from natural and unnatural causes among ECT recipients compared with other psychiatric in-patients over a 25-year period.
Register-based cohort study of all in-patients admitted to a psychiatric hospital from 1976 to 2000. Cause-specific mortality was analysed using log-linear Poisson regression.
There were 783 deceased in-patients who had received ECT compared with 5781 who had not. Patients who had received ECT had a lower overall mortality rate from natural causes (RR=0.82, 95% CI 0.74-0.90) but a slightly higher suicide rate (RR=1.20, 95% CI 0.99-1.47), especially within the first 7 days after the last ECT treatment (RR=4.82, 95% CI 2.12-10.95).
Further investigation of the effect of ECT on physical health and the observed increased suicide rate immediately following treatment are needed, although the last finding is likely to result from selection bias.
关于电休克治疗（ECT）所致死亡率的研究较少。
评估在25年期间，与其他精神科住院患者相比，接受ECT治疗者因自然和非自然原因导致的死亡风险。
基于登记的队列研究，纳入了1976年至2000年期间入住一家精神病医院的所有住院患者。使用对数线性泊松回归分析特定病因死亡率。
接受ECT治疗的住院患者中有783人死亡，未接受ECT治疗的有5781人死亡。接受ECT治疗的患者自然原因导致的总体死亡率较低（相对风险[RR]=0.82，95%置信区间[CI]0.74 - 0.90），但自杀率略高（RR=1.20，95%CI0.99 - 1.47），尤其是在最后一次ECT治疗后的前7天内（RR=4.82，95%CI2.12 - 10.95）。
尽管最后一项发现可能是由选择偏倚导致的，但仍需要进一步研究ECT对身体健康的影响以及治疗后立即观察到的自杀率上升情况。
