Nguyen Doris, Dyck P James, Daube Jasper R
Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Muscle Nerve. 2007 Nov;36(5):715-20. doi: 10.1002/mus.20795.
A progressive radial neuropathy of unknown etiology despite 1.5T magnetic resonance imaging (MRI) and surgical exploration was identified as an intraneural perineurioma by a localized Tinel's sign, an enlarged radial nerve at the spiral groove by 3.0T MRI, and a fascicular biopsy. The distinction between the initial diagnoses of inflammatory, demyelinating polyneuropathy and perineurioma was made by immunohistochemistry and electron microscopy. A slowly progressing, localized mononeuropathy should include perineurioma in the differential diagnosis.
尽管进行了1.5T磁共振成像(MRI)和手术探查,但病因不明的进行性桡神经病变经局部Tinel征、3.0T MRI显示螺旋沟处桡神经增粗以及束状活检,被确诊为神经内神经束膜瘤。通过免疫组织化学和电子显微镜检查,明确了最初诊断的炎症性脱髓鞘性多发性神经病与神经束膜瘤之间的区别。对于缓慢进展的局限性单神经病,鉴别诊断应包括神经束膜瘤。