McClave Stephen A
Division of Gastroenterology/Hepatology, Department of Medicine, University of Louisville School of Medicine, 550 South Jackson Street, Louisville, KY 40202, USA.
Gastroenterol Clin North Am. 2007 Mar;36(1):65-74, vi. doi: 10.1016/j.gtc.2007.01.002.
The benefit of early enteral nutrition (EN) for the disease process and for patient outcome in severe acute pancreatitis is dramatic. A narrow window of opportunity exists during which there is potential for EN to decrease disease severity and reduce overall complications. Most patients with severe pancreatitis tolerate enteral feeds. Any signs of symptom exacerbation or increasing inflammation in response to EN may be ameliorated by subtle adjustments in the feeding strategy. In this manner, provision of EN represents primary therapy in the management of the patient with acute pancreatitis and is emerging as the gold standard of therapy in nutrition support for this disease process.
早期肠内营养(EN)对重症急性胰腺炎的疾病进程及患者预后的益处显著。存在一个狭窄的时机窗,在此期间EN有降低疾病严重程度和减少总体并发症的潜力。大多数重症胰腺炎患者能够耐受肠内喂养。喂养策略的细微调整可能会改善因EN导致的症状加重或炎症加剧的任何迹象。通过这种方式,提供EN是急性胰腺炎患者管理中的主要治疗方法,并且正成为该疾病营养支持治疗的金标准。