Penny D J, Rigby M L, Redington A N
Department of Paediatric Cardiology, Royal Brompton National Heart and Lung Hospital, London.
Br Heart J. 1991 Nov;66(5):375-8. doi: 10.1136/hrt.66.5.375.
To assess whether regional abnormalities of ventricular function are present in patients after the Fontan operation and to explore the implications of any such abnormalities for ventricular filling.
Prospective study in which 25 patients after the Fontan operation were compared with 25 healthy controls and 12 patients with a univentricular atrioventricular connection, before the Fontan operation.
Doppler echocardiography, with simultaneous electrocardiogram, phonocardiogram, and respirometer.
Isovolumic relaxation time was significantly longer in patients after the Fontan operation than in normal children (p less than 0.001) or the preoperative patients (p = 0.001). Systolic intraventricular flow was detected in 60% of patients after the Fontan operation and in 42% of preoperative patients. After the Fontan operation 80% of patients showed intraventricular flow during isovolumic relaxation compared with 8% of normal children and none of the preoperative patients.
Incoordinate ventricular relaxation is common after the Fontan operation. This may have important implications for ventricular diastolic filling, pulmonary blood flow, and cardiac output in these patients.
评估Fontan手术患者是否存在心室功能的局部异常，并探讨此类异常对心室充盈的影响。
前瞻性研究，将25例Fontan手术患者与25例健康对照者以及12例Fontan手术前的单心室房室连接患者进行比较。
采用多普勒超声心动图，同时记录心电图、心音图和呼吸计。
Fontan手术患者的等容舒张时间显著长于正常儿童（p<0.001）或术前患者（p = 0.001）。60%的Fontan手术患者和42%的术前患者检测到收缩期心室内血流。Fontan手术患者中80%在等容舒张期出现心室内血流，而正常儿童为8%，术前患者均未出现。
Fontan手术后心室不协调舒张很常见。这可能对这些患者的心室舒张充盈、肺血流量和心输出量有重要影响。
