Johnson Karen L
School of Nursing, University of Maryland, 655 W Lombard St, Baltimore, MD 21201, USA.
AACN Adv Crit Care. 2007 Apr-Jun;18(2):167-80; quiz 181-2. doi: 10.1097/01.AACN.0000269260.99169.70.
Critical illness polyneuromyopathy, a complication of critical illness, is a primary axonal degeneration of motor and sensory fibers that leads to skeletal muscle weakness. It significantly contributes to the unexplained difficulty in weaning from mechanical ventilation and to their prolonged rehabilitation and poor quality of life after discharge. This article will discuss the diagnosis of critical illness polyneuromyopathy, identify risk factors, review several pathomechanisms that have been proposed, and discuss the implications for practice.
危重病性多神经肌肉病是危重病的一种并发症，是运动和感觉纤维的原发性轴索性变性，可导致骨骼肌无力。它显著导致了机械通气脱机困难且原因不明，以及患者康复时间延长和出院后生活质量差。本文将讨论危重病性多神经肌肉病的诊断，确定危险因素，回顾已提出的几种发病机制，并探讨其对临床实践的意义。
