Rosier-van Dunné F M F, van Wezel-Meijler G, Odendaal H J, van Geijn H P, de Vries J I P
Institute of Fundamental and Clinical Human Movement Sciences, Department of Obstetrics and Gynaecology, VU University Medical Centre, Amsterdam, The Netherlands.
Ultrasound Obstet Gynecol. 2007 Jun;29(6):644-50. doi: 10.1002/uog.4010.
To study the incidence of echodensities in the periventricular white matter, ventricular system, basal ganglia and thalamus of the brain in fetuses at risk for preterm delivery.
This was a prospective study of 124 fetuses with a gestational age between 26 and 34 weeks in pregnancies affected by either pregnancy-induced hypertensive disorders or preterm labor. Transvaginal ultrasound examination of the fetal brain in coronal and sagittal planes was performed weekly until delivery and the neonatal brain was examined within 24 h after delivery.
In 66% of all fetuses, echodensities were found in one or more areas of the brain. They were present in the periventricular area in 52% of cases, the intraventricular area in 18% and in the basal ganglia and thalamus area in 28%. Changes in echogenicity were seen throughout the entire gestational-age period studied. Of the periventricular echodensities that exceeded in echodensity that of the choroid plexus, at least 50% persisted after delivery; at least 38% of the intraventricular echodensities and at least 32% of the basal ganglia and thalamus echodensities persisted after delivery.
In high-risk fetuses, echodensities are a frequent finding in several areas in the brain. How far these echodensities are related to future outcome of the infant needs to be investigated.
研究有早产风险胎儿脑室内白质、脑室系统、基底神经节和丘脑回声密度的发生率。
这是一项对124例孕周在26至34周之间的胎儿进行的前瞻性研究，这些胎儿的母亲患有妊娠高血压疾病或早产。每周经阴道超声检查胎儿脑的冠状面和矢状面，直至分娩，并在分娩后24小时内检查新生儿脑。
在所有胎儿中，66%在脑的一个或多个区域发现回声密度。52%的病例出现在脑室周围区域，18%出现在脑室内区域，28%出现在基底神经节和丘脑区域。在整个研究的孕周期间均可见回声性变化。在脑室周围回声密度超过脉络丛回声密度的病例中，至少50%在分娩后持续存在；至少38%的脑室内回声密度和至少32%的基底神经节和丘脑回声密度在分娩后持续存在。
在高危胎儿中，脑内多个区域经常发现回声密度。这些回声密度与婴儿未来结局的关联程度有待研究。
