Horne Garnet, Ming-Lum Corey, Kirkpatrick Andrew W, Parker Robin L
Departments of Pathology & Laboratory Medicine, University of Calgary, and Calgary Laboratory Services, Calgary, Alberta, Canada.
Int J Surg Pathol. 2007 Apr;15(2):187-91. doi: 10.1177/1066896906295777.
Gastric duplication cysts are rare congenital anomalies that are mostly discovered in children but can remain asymptomatic and undetected into adulthood. Malignant transformation in gastric duplications is extremely rare, with most reported cases being adenocarcinomas. Herein, the authors report the first case of a high-grade neuroendocrine carcinoma arising in a gastric duplication cyst in a 40-year-old Asian male. This case highlights that duplication cysts should be included in the differential diagnosis of cystic masses of the gastrointestinal tract in adult, as well as pediatric, patients and emphasizes the importance of complete surgical resection and meticulous pathologic examination of these congenital anomalies.
胃重复囊肿是罕见的先天性异常，大多在儿童期被发现，但也可能无症状，直至成年期仍未被发现。胃重复囊肿发生恶性转化极为罕见，大多数报道的病例为腺癌。在此，作者报告首例发生于一名40岁亚洲男性胃重复囊肿的高级别神经内分泌癌。该病例强调，在成人及儿童患者胃肠道囊性肿物的鉴别诊断中应考虑重复囊肿，并强调对这些先天性异常进行完整手术切除及细致病理检查的重要性。
