Gozke E, Ozyurt Z, Dortcan N, Ore O, Kocer A, Ozer E
Department of Neurology, FSM Teaching and Research Hospital, Istanbul, Turkey.
Electromyogr Clin Neurophysiol. 2007 Mar-Apr;47(2):117-21.
The aim of this study was to investigate the disorders of sympathetic nervous system in patients with hyperthyroidism using sympathetic skin response (SSR).
Twenty-two newly diagnosed cases with hyperthyroidism were included in the study. The results were compared with those of 20 healthy controls. SSR was recorded with the contralateral electrical stimulation of the median nerve (of the upper extremities) and tibial nerve (of the lower extremities) with active electrodes placed on palms and soles and reference electrodes attached on the dorsal aspects of hands and feet.
Ages of the cases with hyperthyroidism and controls ranged between 15-65 years (mean: 46.7 +/- 15.0 years) and 24-62 years (mean: 39.6 +/- 9.8 years) respectively (p > 0.05). In all the control subjects SSR could be obtained, while from the lower extremities of 4 cases with hyperthyroidism (18.0%) SSR could not be elicited. Mean SSR latencies of lower extremities were found significantly longer than control group (p < 0. 05). No difference was detected between mean amplitudes of SSR in upper and lower extremities.
These findings suggest that SSR is useful for investigation of sympathetic nervous system involvement in cases with hyperthyroidism.
本研究旨在利用交感神经皮肤反应（SSR）探究甲状腺功能亢进症患者的交感神经系统紊乱情况。
本研究纳入22例新诊断的甲状腺功能亢进症患者。将结果与20名健康对照者的结果进行比较。通过对正中神经（上肢）和胫神经（下肢）进行对侧电刺激来记录SSR，将活动电极置于手掌和脚底，参考电极附着于手和脚的背侧。
甲状腺功能亢进症患者和对照者的年龄分别在15 - 65岁（平均：46.7±15.0岁）和24 - 62岁（平均：39.6±9.8岁）之间（p>0.05）。所有对照者均可获得SSR，而4例甲状腺功能亢进症患者（18.0%）下肢无法引出SSR。发现下肢SSR的平均潜伏期明显长于对照组（p<0.05）。上肢和下肢SSR的平均波幅之间未检测到差异。
这些发现表明SSR有助于研究甲状腺功能亢进症患者交感神经系统受累情况。
