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Review on the transmission porcine reproductive and respiratory syndrome virus between pigs and farms and impact on vaccination.猪繁殖与呼吸综合征病毒在猪群及猪场间的传播及其对疫苗接种影响的综述
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Infectiousness of pigs infected by the Porcine Reproductive and Respiratory Syndrome virus (PRRSV) is time-dependent.猪感染猪繁殖与呼吸综合征病毒(PRRSV)后的传染性是时间依赖性的。
Vet Res. 2012 Oct 12;43(1):69. doi: 10.1186/1297-9716-43-69.

本文引用的文献

1
Evaluation of the effects of animal age, concurrent bacterial infection, and pathogenicity of porcine reproductive and respiratory syndrome virus on virus concentration in pigs.评估动物年龄、并发细菌感染以及猪繁殖与呼吸综合征病毒的致病性对猪体内病毒浓度的影响。
Am J Vet Res. 2006 Mar;67(3):489-93. doi: 10.2460/ajvr.67.3.489.
2
Probability of porcine reproductive and respiratory syndrome (PRRS) virus infection as a function of exposure route and dose.猪繁殖与呼吸综合征(PRRS)病毒感染概率与暴露途径和剂量的关系。
Vet Microbiol. 2005 Sep 30;110(1-2):7-16. doi: 10.1016/j.vetmic.2005.06.012.
3
Emergence of a convex trade-off between transmission and virulence.传播与毒力之间出现凸性权衡。
Am Nat. 2005 Jun;165(6):E155-67. doi: 10.1086/430053. Epub 2005 Mar 24.
4
Pathogenic and humoral immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) are related to viral load in acute infection.对猪繁殖与呼吸综合征病毒(PRRSV)的致病性和体液免疫反应与急性感染中的病毒载量有关。
Vet Immunol Immunopathol. 2004 Dec 8;102(3):233-47. doi: 10.1016/j.vetimm.2004.09.010.
5
Challenging the trade-off model for the evolution of virulence: is virulence management feasible?挑战毒力进化的权衡模型:毒力管理是否可行?
Trends Microbiol. 2003 Jan;11(1):15-20. doi: 10.1016/s0966-842x(02)00003-3.
6
Assessing the duration of persistence and shedding of porcine reproductive and respiratory syndrome virus in a large population of breeding-age gilts.评估猪繁殖与呼吸综合征病毒在大量育龄后备母猪群体中的持续存在时间和排毒情况。
Can J Vet Res. 2002 Jul;66(3):196-200.
7
A quantitative assessment of the effectiveness of PRRSV vaccination in pigs under experimental conditions.
Vaccine. 2001 Jun 14;19(27):3636-44. doi: 10.1016/s0264-410x(01)00099-8.
8
Effect of challenge dose and route on porcine reproductive and respiratory syndrome virus (PRRSV) infection in young swine.攻毒剂量和途径对幼猪感染猪繁殖与呼吸综合征病毒(PRRSV)的影响。
Vet Res. 1999 Nov-Dec;30(6):629-38.
9
Porcine reproductive and respiratory syndrome virus: routes of excretion.猪繁殖与呼吸综合征病毒:排泄途径
Vet Microbiol. 1997 Jun 30;57(1):69-81. doi: 10.1016/s0378-1135(97)00079-5.
10
The influence of maternal immunity on the transmission of pseudorabies virus and on the effectiveness of vaccination.母体免疫对伪狂犬病病毒传播及疫苗接种效果的影响。
Vaccine. 1997 Feb;15(3):287-94. doi: 10.1016/s0264-410x(96)00179-x.

Experimental quantification of the transmission of Porcine reproductive and respiratory syndrome virus.

作者信息

Mondaca-Fernández Enrique, Meyns Tom, Muñoz-Zanzi Claudia, Trincado Carlos, Morrison Robert B

机构信息

Swine Disease Eradication Center, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA.

出版信息

Can J Vet Res. 2007 Apr;71(2):157-60.

PMID:17479780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1829187/
Abstract

We conducted an experiment to determine the ability of vaccine against Porcine reproductive and respiratory syndrome virus (PRRSV) to reduce the transmission of PRRSV among pigs. At the end of the experiment, transmission rates did not differ significantly (P = 0.61) between the vaccinated and nonvaccinated pigs, the mean R-values being 0.598 (95% confidence interval [CI] 0.136 to 3.218) and 0.264 (95% CI 0.008 to 2.266), respectively. The unusually low rate of PRRSV transmission in both groups may not have provided a sufficient challenge to detect a vaccine effect. Several factors could affect the rate of PRRSV transmission: isolate virulence, inoculation dose, inoculation route, number of passages of the challenge virus in cell culture, and population size. Of these, isolate virulence appears to be the most important factor associated with the low transmissibility observed in this study. More studies comparing rates of transmission between PRRSV isolates with diverse levels of virulence are needed to better understand this association.

摘要