Popeney Charles, Ansell Van, Renney Ken
Fort Bend Neurology, Sugar Land, Texas 77479, USA.
Neurourol Urodyn. 2007;26(6):820-7. doi: 10.1002/nau.20421.
This study was conducted to evaluate pudendal entrapment as an etiology of chronic pain, a diagnostic protocol for pudendal entrapment, and clinical response to surgical decompression.
A case series of 58 consecutive patients with a diagnosis of pudendal entrapment, based on clinical factors, neurophysiologic studies, and response to pudendal nerve infiltrations, is described. All patients were refractory to other treatment modalities. Patients were assessed before and after surgical decompression: degree of pain was assessed by visual analog scale (VAS) score, percent global overall improvement, and improved function and quality of life before surgery and 12 months or longer after surgery.
The primary presenting feature was progressive, chronic, intractable neuropathic pain in the perineum (ano-rectal and/or urogenital) that worsened with sitting. Other symptoms included urinary hesitancy, frequency, urgency, constipation/painful bowel movements, and sexual dysfunction. After surgical decompression, 35 (60%) patients were classified as responders, based on one of the following three criteria: a greater than 50% reduction in VAS score, a greater than 50% improvement in global assessment of pain, or a greater than 50% improvement in function and quality of life.
Pudendal entrapment can be a cause of chronic, disabling perineal pain in both men and women. Since symptomatic patients seek medical care from many different medical specialists, a reliable diagnostic protocol should be established. For patients refractory to conventional interventions, surgical decompression of the pudendal nerve can improve pain-related symptoms and disability. With ongoing work on this subject, which is a difficult disorder to accurately diagnose and treat, a better awareness of pudendal entrapment across specialties will emerge.
本研究旨在评估阴部神经卡压作为慢性疼痛的病因、阴部神经卡压的诊断方案以及手术减压的临床反应。
描述了一系列连续的58例诊断为阴部神经卡压的患者,诊断基于临床因素、神经生理学研究以及对阴部神经浸润的反应。所有患者对其他治疗方式均无效。在手术减压前后对患者进行评估:通过视觉模拟量表(VAS)评分评估疼痛程度、总体改善百分比,并比较手术前以及手术后12个月或更长时间的功能和生活质量改善情况。
主要表现特征为会阴部(肛门直肠和/或泌尿生殖区域)进行性、慢性、顽固性神经性疼痛,坐位时加重。其他症状包括排尿犹豫、尿频、尿急、便秘/排便疼痛以及性功能障碍。手术减压后,35例(60%)患者根据以下三项标准之一被归类为反应者:VAS评分降低超过50%、疼痛总体评估改善超过50%或功能和生活质量改善超过50%。
阴部神经卡压可能是男性和女性慢性、致残性会阴部疼痛的原因。由于有症状的患者会向许多不同的医学专科医生寻求治疗,因此应建立可靠的诊断方案。对于对传统干预措施无效的患者,阴部神经手术减压可改善与疼痛相关的症状和功能障碍。随着对这一难以准确诊断和治疗的疾病的持续研究,各专科对阴部神经卡压的认识将得到提高。