进行性核上性麻痹患者中脑桥臂在液体衰减反转恢复序列上的信号变化。

Signal changes of superior cerebellar peduncle on fluid-attenuated inversion recovery in progressive supranuclear palsy.

作者信息

Kataoka Hiroshi, Tonomura Yasuyo, Taoka Toshiaki, Ueno Satoshi

机构信息

Department of Neurology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan.

出版信息

Parkinsonism Relat Disord. 2008;14(1):63-5. doi: 10.1016/j.parkreldis.2007.03.001. Epub 2007 May 4.

DOI:10.1016/j.parkreldis.2007.03.001

PMID:17481936

Abstract

Pathological changes of the superior cerebellar peduncle (SCP) can occur in PSP. We assessed the clinical history and signal changes in the SCP on fluid-attenuated inversion recovery (FLAIR) images of 12 patients with clinically probable PSP. Three control groups were studied: Parkinson's disease (PD), multiple system atrophy with predominant parkinsonian features (MSA-P), and healthy controls. Three patients who had clinically probable PSP showed increased FLAIR signals within the SCP. No subject with PD or MSA-P showed any signal changes of the SCP. The signal changes in the SCP on FLAIR may be one indicator for differentiating PSP from other parkinsonian diseases.

摘要

上小脑脚（SCP）的病理改变可发生于进行性核上性麻痹（PSP）。我们评估了12例临床疑似PSP患者的临床病史以及SCP在液体衰减反转恢复（FLAIR）图像上的信号变化。研究了三个对照组：帕金森病（PD）、以帕金森综合征为主要特征的多系统萎缩（MSA-P）和健康对照。3例临床疑似PSP患者的SCP内FLAIR信号增强。PD或MSA-P患者均未出现SCP的任何信号变化。SCP在FLAIR图像上的信号变化可能是鉴别PSP与其他帕金森病的一个指标。