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马尾神经转移性血管外皮细胞瘤:一例报告

Metastatic hemangiopericytoma to the cauda equina: a case report.

作者信息

Taniura Seijiro, Taniguchi Makoto, Mizutani Toshio, Takahashi Hiroshi

机构信息

Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Tokyo 183-0042, Japan.

出版信息

Spine J. 2007 May-Jun;7(3):371-3. doi: 10.1016/j.spinee.2006.05.011. Epub 2006 Nov 20.

Abstract

BACKGROUND CONTEXT

Hemangiopericytoma is an aggressive tumor associated with high recurrence and metastasis. Metastases are usually delayed, long after diagnosis of the primary lesion. Metastatic hemangiopericytoma to the spinal cord is especially rare.

PURPOSE

To report a rare clinical presentation of a metastatic intradural, intramedullary hemangiopericytoma to the cauda equina from a cerebellar hemangiopericytoma.

STUDY DESIGN

Case report with a review of the literature.

METHODS

Clinical history, physical findings, and magnetic resonance imaging studies of a patient with a metastatic intradural, intramedullary hemangiopericytoma to the cauda equina are reported.

RESULTS

A case report is presented of a female with an intradural, intramedullary lesion at the L4-S1 level, presenting initially with progressive pain and motor weakness affecting the left lower extremity. She had a history of a cerebellar hemangiopericytoma, which had been treated with total resection and radiotherapy 4 years earlier. This patient developed urinary urgency and frequency. Pathological analysis revealed a hemangiopericytoma, which had a similar character to a cerebellar lesion. After radiotherapy, the tumor was mostly diminished and her symptoms totally resolved.

CONCLUSIONS

Hemangiopericytomas have a strong tendency to both local recurrence and metastasis. Common metastatic sites are the skeletal system, lung, liver, and abdominal cavity. To the authors' knowledge, there have been no reports of spinal intradural, intramedullary metastasis of hemangiopericytoma.

摘要

背景

血管外皮细胞瘤是一种侵袭性肿瘤,具有高复发和转移率。转移通常延迟发生,在原发性病变诊断后很长时间才出现。脊髓转移的血管外皮细胞瘤尤为罕见。

目的

报告一例罕见的临床病例,即小脑血管外皮细胞瘤转移至马尾的硬脊膜内、髓内血管外皮细胞瘤。

研究设计

病例报告并文献复习。

方法

报告一例硬脊膜内、髓内血管外皮细胞瘤转移至马尾患者的临床病史、体格检查结果及磁共振成像研究。

结果

报告一例女性患者,L4 - S1水平存在硬脊膜内、髓内病变,最初表现为进行性疼痛和影响左下肢的运动无力。她有小脑血管外皮细胞瘤病史,4年前已接受全切除和放疗。该患者出现尿急和尿频。病理分析显示为血管外皮细胞瘤,其特征与小脑病变相似。放疗后,肿瘤大部分缩小,症状完全缓解。

结论

血管外皮细胞瘤有很强的局部复发和转移倾向。常见转移部位为骨骼系统、肺、肝和腹腔。据作者所知,尚无血管外皮细胞瘤脊髓硬脊膜内、髓内转移的报道。

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