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阿尔茨海默病中的动词习得与表征

Verb acquisition and representation in Alzheimer's disease.

作者信息

Grossman Murray, Murray Ryan, Koenig Phyllis, Ash Sherry, Cross Katy, Moore Peachie, Troiani Vanessa

机构信息

Department of Neurology, University of Pennsylvania School of Medicine, USA.

出版信息

Neuropsychologia. 2007 Jun 18;45(11):2508-18. doi: 10.1016/j.neuropsychologia.2007.03.020. Epub 2007 Mar 30.

DOI:10.1016/j.neuropsychologia.2007.03.020
PMID:17482652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1986669/
Abstract

We examined the implicit acquisition and mental representation of a novel verb in patients with probable Alzheimer's disease (AD). Patients were exposed to the new verb in a naturalistic manner as part of a simple picture story. We probed grammatical, semantic and thematic matrix knowledge of the verb soon after presentation and again 1 week later. We found partial verb acquisition that was retained over 1 week. AD patients did not differ from controls in their acquisition and retention of a new verb's major grammatical subcategory, although they acquired little of its semantic properties and displayed minimal acquisition of the new word's thematic matrix. Moreover, AD patients appeared to maintain their acquired grammatical knowledge over 1 week. We discuss the implications of these findings from several perspectives, including the modularity of the language processing system, the relationship between episodic memory and semantic memory, and the role of the preserved implicit memory system in AD patients' partially successful lexical acquisition.

摘要

我们研究了可能患有阿尔茨海默病(AD)的患者对一个新动词的隐性习得和心理表征。作为一个简单图片故事的一部分,患者以自然主义的方式接触这个新动词。在呈现新动词后不久以及1周后,我们探究了该动词的语法、语义和主题矩阵知识。我们发现了部分动词习得,且这种习得在1周后仍得以保留。AD患者在新动词主要语法子类别的习得和保留方面与对照组没有差异,尽管他们几乎没有习得其语义属性,并且对新单词的主题矩阵的习得也很少。此外,AD患者似乎在1周内保持了他们习得的语法知识。我们从几个角度讨论了这些发现的意义,包括语言处理系统的模块性、情景记忆和语义记忆之间的关系,以及保留的隐性记忆系统在AD患者部分成功的词汇习得中的作用。

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本文引用的文献

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Temporally graded semantic memory loss in amnesia and semantic dementia: Further evidence for opposite gradients.遗忘症和语义性痴呆的时间梯度语义记忆丧失:相反梯度的进一步证据。
Cogn Neuropsychol. 2002 Mar 1;19(2):135-63. doi: 10.1080/02643290143000123.
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Lexical acquisition in progressive aphasia and frontotemporal dementia.进行性失语症和额颞叶痴呆中的词汇习得
Cogn Neuropsychol. 2007 Feb;24(1):48-69. doi: 10.1080/02643290600890657.
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