Paick Jae-Seung, Um Jin Mo, Kwak Cheol, Kim Soo Woong, Ku Ja Hyeon
Department of Urology, Seoul National University Hospital, Seoul, Korea.
Urology. 2007 May;69(5):859-63. doi: 10.1016/j.urology.2007.01.042.
To determine the effect of bladder contractility on the outcomes of high-power (80 W) potassium-titanyl-phosphate laser vaporization of the prostate in men with lower urinary tract symptoms.
A total of 68 men with a median age of 68.5 years (range 53 to 86) were included in the study. The median follow-up was 9 months (range 6 to 21).
The median International Prostate Symptom Score and quality-of-life index decreased from 18 to 8.5 (P <0.001) and from 4 to 2 (P <0.001), respectively. The median maximal flow rate increased from 10 to 16.1 mL/s (P <0.001) and the median postvoid residual urine volume decreased from 28 to 10 mL (P <0.001). No differences were found in the change in the International Prostate Symptom Score or maximal flow rate according to age, prostate volume, or bladder outlet obstruction index. The weak bladder contractility index (BCI) group (BCI less than 100) had a smaller decrease in the median International Prostate Symptom Score and a smaller increase in the maximal flow rate than did those in the higher BCI group (BCI of 100 or more; P = 0.047 and P = 0.035, respectively). The baseline clinical parameters, including age, prostate volume, serum prostate-specific antigen, and bladder outlet obstruction index, were not significantly different between the low and greater BCI groups.
The results of the present study have shown that after high-power potassium-titanyl-phosphate laser vaporization, patients with weak bladder contractility had less subjective and objective improvement than did those patients with normal or strong bladder contractility.
确定膀胱收缩力对下尿路症状男性患者进行高功率(80W)磷酸钛钾激光前列腺汽化术疗效的影响。
本研究共纳入68名男性,中位年龄为68.5岁(范围53至86岁)。中位随访时间为9个月(范围6至21个月)。
国际前列腺症状评分中位数和生活质量指数分别从18降至8.5(P<0.001)和从4降至2(P<0.001)。最大尿流率中位数从10增至16.1mL/s(P<0.001),排尿后残余尿量中位数从28降至10mL(P<0.001)。根据年龄、前列腺体积或膀胱出口梗阻指数,国际前列腺症状评分或最大尿流率的变化未发现差异。膀胱收缩力弱指数(BCI)组(BCI小于100)的国际前列腺症状评分中位数下降幅度小于BCI较高组(BCI为100或更高),最大尿流率增加幅度也小于BCI较高组(分别为P=0.047和P=0.035)。低BCI组和高BCI组之间的基线临床参数,包括年龄、前列腺体积、血清前列腺特异性抗原和膀胱出口梗阻指数,无显著差异。
本研究结果表明,高功率磷酸钛钾激光汽化术后,膀胱收缩力弱的患者主观和客观改善程度低于膀胱收缩力正常或强的患者。