来自小鼠H-2K区域的胚胎表达基因KE2的一级结构。

Primary structure of the embryo-expressed gene KE2 from the mouse H-2K region.

作者信息

Ha H, Abe K, Artzt K

机构信息

Department of Zoology, University of Texas, Austin 78712-1064.

出版信息

Gene. 1991 Nov 15;107(2):345-6. doi: 10.1016/0378-1119(91)90339-d.

DOI:10.1016/0378-1119(91)90339-d

PMID:1748305

Abstract

Nucleotide (nt) sequence of the KE2 wild-type (wt) cDNA revealed a novel 669-bp open reading frame encoding a putative hydrophilic protein of 127 amino acids, pI 6.17. Comparison of the wt to the genomic nt sequence from the tw5 mutant shows the KE2 gene is conserved and is probably a functional gene unrelated to the tw5 lethality.

摘要

KE2野生型（wt）cDNA的核苷酸（nt）序列揭示了一个新的669碱基对的开放阅读框，编码一个由127个氨基酸组成的假定亲水性蛋白，其等电点为6.17。将wt与tw5突变体的基因组nt序列进行比较，结果表明KE2基因是保守的，可能是一个与tw5致死性无关的功能基因。