Zhang S, Xu S, Li G, Su Z, Liu W, Xie Q, Zhang J, Zhang Z, Qian Y, Shen J
Department of Pathology, Chongqing University of Medical Sciences.
Hua Xi Yi Ke Da Xue Xue Bao. 1991 Sep;22(3):307-10.
Two hundred forty-nine cases of non-Hodgkin's lymphomas (NHL) were reviewed by using the working classification of NHL (Chengdu, 1985). The results showed that the patients of 249 cases of NHL ranging in age from 5 to 76 years, with the mean age of 42 of the types were separated into three major prognostic groupings as follows: 1. low (41 of 249 cases, small lymphocytic 27 cases, lymphoplasmacytoid 2 cases, follicular cleaved 7 cases, follicular cleaved and noncleaved 5 cases); 2. intermediate (58 of 249 cases, diffuse cleaved 28 cases, diffuse cleaved and noncleaved 27 cases, follicular noncleaved 3 cases); and 3. high grade malignancy (150 of 249 cases, diffuse noncleaved 49 cases, lymphoblastic 41 cases, immunoblastic 13 cases, polymorphic 39 cases, clear cell 2 cases, histiocytic 6 cases). Each group was significantly different from the others (P less than 0.05). The prognosis of patients with angioimmunoblastic lymphadenopathy like T-cell lymphoma (9 of 249 cases) was not more significant (P greater than 0.05) than that of patients with other polymorphic lymphoma (30 of 249 cases). The results showed this Chengdu classification of NHL is good for practice and usage in clinical evaluation and routine surgical pathology.
采用非霍奇金淋巴瘤（NHL）工作分类法（成都，1985年）对249例非霍奇金淋巴瘤病例进行了回顾性分析。结果显示，249例NHL患者年龄在5至76岁之间，平均年龄为42岁，其病理类型分为以下三个主要预后分组：1. 低危组（249例中的41例，小淋巴细胞型27例，淋巴浆细胞型2例，滤泡性裂细胞型7例，滤泡性裂细胞与非裂细胞混合型5例）；2. 中危组（249例中的58例，弥漫性裂细胞型28例，弥漫性裂细胞与非裂细胞混合型27例，滤泡性非裂细胞型3例）；3. 高危恶性组（249例中的150例，弥漫性非裂细胞型49例，淋巴母细胞型41例，免疫母细胞型13例，多形性39例，透明细胞型2例，组织细胞型6例）。各组之间差异有统计学意义（P<0.05）。血管免疫母细胞性淋巴结病样T细胞淋巴瘤患者（249例中的9例）的预后与其他多形性淋巴瘤患者（249例中的30例）相比，差异无统计学意义（P>0.05）。结果表明，这种成都NHL分类法在临床评估和常规手术病理中便于实际应用。
