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术中γ探头引导下的腹腔镜副脾切除术

Laparoscopic accessory splenectomy using intraoperative gamma probe guidance.

作者信息

Kirshtein Boris, Lantsberg S, Hatskelzon L, Lantsberg L

机构信息

Department of Surgery A, Soroka University Medical Center, Beer-Sheva, Israel.

出版信息

J Laparoendosc Adv Surg Tech A. 2007 Apr;17(2):205-8. doi: 10.1089/lap.2006.0083.

Abstract

In cases of accessory splenic tissue in postsplenectomy patients, it is of utmost importance to localize the accessory spleen prior to surgery. Several studies have shown the feasibility of laparoscopic resection of accessory splenic tissue using preoperative scintigraphy. We present the cases of three postsplenectomy patients with accessory splenic tissue causing relapsing hematologic disease. Accessory spleens were diagnosed and localized preoperatively by positive uptake of heat-damaged Tc99m-labeled red blood cells using scintigraphy. Two patients with relapse of immune thrombocytopenic purpura and one with hemolytic anemia underwent handheld gamma probe-assisted laparoscopic accessory splenectomy. One patient with immune thrombocytopenic purpura recovered his platelet count at 3-year follow-up. The other patient had a relapse of disease within 3 months despite successful removal of the accessory spleen. The patient with hemolytic anemia had postoperative relapse; two accessory spleens were identified on radionuclide investigation. The use of intraoperative nuclear imaging can greatly aid in localization and provide confirmation of complete laparoscopic excision of the nuclear focus. The technique is especially useful in cases of a small accessory spleen, by avoiding a major open procedure and contributing to good postoperative results.

摘要

对于脾切除术后出现副脾组织的患者,在手术前定位副脾至关重要。多项研究表明,术前使用闪烁扫描法对副脾组织进行腹腔镜切除是可行的。我们报告了3例脾切除术后因副脾组织导致血液系统疾病复发的患者。术前通过闪烁扫描法检测到热损伤的Tc99m标记红细胞摄取阳性,从而诊断并定位了副脾。2例免疫性血小板减少性紫癜复发患者和1例溶血性贫血患者接受了手持γ探针辅助的腹腔镜副脾切除术。1例免疫性血小板减少性紫癜患者在3年随访时血小板计数恢复正常。另1例患者尽管成功切除了副脾,但在3个月内疾病复发。溶血性贫血患者术后复发;放射性核素检查发现了2个副脾。术中使用核成像技术可极大地帮助定位,并确认腹腔镜完全切除核灶。该技术在副脾较小的情况下特别有用,可避免进行大型开放手术,并有助于取得良好的术后效果。

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