Lekamwasam Sarath, Rodrigo Mahinda, Arachchi Wasantha Kodikara, Munidasa Duminda
Center for Metabolic Bone Diseases, Faculty of Medicine, Galle, Sri Lanka.
J Clin Densitom. 2007 Apr-Jun;10(2):170-3. doi: 10.1016/j.jocd.2007.01.007. Epub 2007 Mar 26.
Although it is generally recommended that patients keep their hips flexed by 90 degrees during the measurement of spinal bone mineral density (BMD), there is no uniform agreement among the manufacturers of dual-energy X-ray absorptiometry (DXA) scanners regarding the positioning of legs while scanning the spine. We measured spinal BMD in 54 postmenopausal women, from L1 to L4 in posterior-anterior projection, using a Hologic Discovery scanner, first with their legs elevated as recommended by the manufacturer and then with their legs flat on the scanning table. Differences of bone mineral content (BMC), area of the region of interest (ROI), BMD, and T-score of the total spine between the 2 scans were compared. The mean (SD) age of the women was 54.3 yr (15 yr). Between the 2 scans, BMC, area of the ROI, BMD, and T-scores showed high correlations (r=0.98, 0.94, 0.99, and 0.99, respectively). BMC and the area of the ROI changed significantly between the 2 scans, but the changes of BMD and T-scores were not significant. The percentage changes of BMC and the area of the ROI were similar (2.6% and 2.4%, respectively), whereas T-scores showed no change and change of BMD was only 0.6%. The absolute difference in BMD between the 2 scans was only 0.005 (p=0.09). When spinal BMD was measured with their legs elevated, 31 women were found to have osteoporosis and further 13 were found to have osteopenia. When spinal BMD was measured with their legs flat, 32 women were found to have osteoporosis and further 12 were found to have osteopenia. In conclusion, no clinically or statistically significant difference in the total spinal BMD was found when the BMD in a group of women was measured on a Hologic Discovery DXA scanner with their legs positioned flat.
虽然一般建议患者在测量脊柱骨密度(BMD)时将髋关节屈曲90度,但双能X线吸收仪(DXA)扫描仪制造商对于扫描脊柱时腿部的定位并未达成统一意见。我们使用Hologic Discovery扫描仪,对54名绝经后女性进行了脊柱BMD测量,扫描方向为前后位,从L1至L4,首先按照制造商的建议抬高她们的双腿,然后让她们的双腿平放在扫描台上。比较了两次扫描之间全脊柱的骨矿物质含量(BMC)、感兴趣区域(ROI)面积、BMD和T值的差异。这些女性的平均(标准差)年龄为54.3岁(15岁)。两次扫描之间,BMC、ROI面积、BMD和T值显示出高度相关性(分别为r = 0.98、0.94、0.99和0.99)。两次扫描之间,BMC和ROI面积有显著变化,但BMD和T值的变化不显著。BMC和ROI面积的百分比变化相似(分别为2.6%和2.4%),而T值没有变化,BMD的变化仅为0.6%。两次扫描之间BMD的绝对差异仅为0.005(p = 0.09)。当抬高双腿测量脊柱BMD时,发现31名女性患有骨质疏松症,另有13名女性患有骨质减少症。当双腿平放在扫描台上测量脊柱BMD时,发现32名女性患有骨质疏松症,另有12名女性患有骨质减少症。总之,在一组女性中,使用Hologic Discovery DXA扫描仪将双腿平放在扫描台上测量脊柱BMD时,未发现全脊柱BMD存在临床或统计学上的显著差异。