Raghavan Sathees C, Lieber Michael R
Department of Biochemistry, Indian Institute of Science, Bangalore, India.
Front Biosci. 2007 May 1;12:4402-8. doi: 10.2741/2397.
Recently, multiple lines of evidences have shown that non-B DNA structures within the human genes may lead to chromosomal translocations, deletions and amplifications in cancer and other human diseases. In this review, we summarize the current literature on non-B DNA structures, and discuss their role in genomic instability and diseases.
