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先天性梅毒真的是先天性梅毒吗?

Is congenital syphilis really congenital syphilis?

作者信息

Li Yi, Gonik Bernard

机构信息

Department of Obstetrics and Gynecology, School of Medicine, Wayne State University, Detroit, MI 48235, USA.

出版信息

Infect Dis Obstet Gynecol. 2006;2006:81629. doi: 10.1155/IDOG/2006/81629.

Abstract

Detroit has recently been distinguished as having the highest congenital syphilis rate in the United States (250.3 cases per 100 000 live births in Detroit versus 10.3 in the US). However, depending on each health department's followup and CDC reporting, these data may not accurately reflect the true congenital syphilis rate. This study examines the reported cases over a three-year time period with focus on the criteria used for diagnosis. All local health department congenital syphilis CDC collection forms (form 73.126) were reviewed for the years in question. The reported congenital syphilis cases in the year 2002-2004 in Detroit were reviewed. No cases met confirmed case criteria and few probable cases were based on neonatal evaluations. The majority of "congenital syphilis" cases were established based on incomplete maternal data such as missing followup serologic titers in the absence of complete neonatal information. In conclusion, although the reported congenital syphilis rate in Detroit is alarmingly high, the true occurrence of congenital syphilis is likely to have been overstated. A health department reporting program that includes more diligent neonatal followup would allow for a more accurate representation of this public health concern.

摘要

底特律最近因先天性梅毒发病率在美国最高而受到关注(底特律每10万例活产中有250.3例,而美国为10.3例)。然而,根据各卫生部门的随访情况和疾病控制与预防中心(CDC)的报告,这些数据可能无法准确反映先天性梅毒的实际发病率。本研究调查了三年期间报告的病例,重点关注诊断标准。对相关年份所有地方卫生部门的先天性梅毒CDC收集表格(表格73.126)进行了审查。对底特律2002年至2004年报告的先天性梅毒病例进行了审查。没有病例符合确诊病例标准,基于新生儿评估的可能病例也很少。大多数“先天性梅毒”病例是根据不完整的母亲数据确定的,比如在没有完整新生儿信息的情况下缺少随访血清学滴度。总之,尽管底特律报告的先天性梅毒发病率高得惊人,但先天性梅毒的实际发生率可能被高估了。一个包括更勤勉新生儿随访的卫生部门报告项目将能更准确地反映这一公共卫生问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/781c/1779614/f07108b8bab3/IDOG2006-81629.001.jpg

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