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脊髓机制在周围性肌阵挛发生中的作用:一例报告。

The contribution of a spinal mechanism in developing peripheral myoclonus: a case report.

作者信息

Shin Hae-Won, Ye Byung S, Kim Jinkwon, Kim Seung M, Sohn Young H

机构信息

Department of Neurology and Brain Research Institute, Yonsei University College of Medicine, Seoul, South Korea.

出版信息

Mov Disord. 2007 Jul 15;22(9):1350-2. doi: 10.1002/mds.21418.

Abstract

Focal myoclonus of peripheral origin, i.e., peripheral myoclonus (PM), is a rare disorder. Although PM always accompanies a lesion in the peripheral nerve, supplying the affected muscles, its mechanism remains unclear. Here we present a patient with focal myoclonus of the thigh muscles following a traumatic lesion in the femoral nerve. Lumbar spinal anesthesia, as well as local anesthetic block of the femoral nerve, completely abolished the patient's myoclonus temporarily. This movement was remarkably diminished after a surgical exploration of the wound with the removal of fibrous tissue beneath the scar and liberation of the femoral nerve. This case suggests the contribution of a spinal relay mechanism in the development of PM, in addition to the contribution of a nerve lesion.

摘要

周围性起源的局灶性肌阵挛,即周围性肌阵挛(PM),是一种罕见的疾病。尽管PM总是伴随着支配受影响肌肉的周围神经病变,但其机制仍不清楚。在此,我们报告一名患者,在股神经遭受创伤性损伤后出现大腿肌肉局灶性肌阵挛。腰椎脊髓麻醉以及股神经局部麻醉均能暂时完全消除患者的肌阵挛。在对伤口进行手术探查,切除瘢痕下的纤维组织并松解股神经后,这种运动明显减少。该病例表明,除神经病变外,脊髓中继机制在PM的发生发展中也起作用。

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