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胆结石的体外溶解

Dissolution of gall-stones in vitro.

作者信息

Modi R P, Jain T C, Baid J C, Maheshwari M

机构信息

Department of Surgery, JLN Medical College, Ajmer.

出版信息

J Indian Med Assoc. 1991 May;89(5):129-32.

PMID:1748778
Abstract

An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while bile salt (sodium desoxycholate) proved better and clofibrate the best solvent in various concentrations used. In addition 3 stones, one from each patient, were placed in normal saline to serve as control.

摘要

对从3名患者身上获取的36颗胆结石(每名患者12颗)进行了体外研究,研究其在不同浓度的肝素、胆盐和氯贝丁酯溶液中的溶解情况。结果发现,肝素是一种较差的溶剂,而胆盐(去氧胆酸钠)在不同浓度下表现较好,氯贝丁酯是最佳溶剂。此外,从每名患者身上各取1颗胆结石置于生理盐水中作为对照。

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1
Dissolution of gall-stones in vitro.胆结石的体外溶解
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2
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